Researchers are changing the game with Google Maps of cells

Where would we be without Google Maps on our mobile phones? Maybe lost.

With just a few clicks of a button, one can be sure they are headed to the right street, find out the nearest grocery store or plan a hike.

Currently, the National Health Trust’s Human Biomolecular Cell Atlas Program – or HuBMAP – is developing a global platform for mapping healthy cells in the human body – Google Maps of your cells.

as described Written by Dr. Graham MacLeod in a research paper published in 2020 for the University of Manitoba Journal of Medicine, “HuBMAP seeks to develop a comprehensive, accessible, three-dimensional molecular and cellular atlas of the human body, in health and under various pathological conditions.”

By bringing together biologists of all types (cellular, molecular, developmental, computational), HuBMAP aims to create an atlas of 37 trillion cells in the human body.

The specific 3D organization of cells affects function, aging and disease progression in various organs and tissues, and the consortium is working to improve the world’s knowledge of this area.

Having a greater understanding at a deeper level will greatly assist clinical researchers and drug developers in developing specialized medical treatments. As Ed Young from The Atlantic said, Article about the projectGeneticists are constantly learning about genes that influence disease risk, but genes don’t operate in a vacuum. They perform in our cells. And since the 30 trillion cells in your body all share the same genes, you need to know which cells actually use the gene in question. Where are those cells? What do they usually do, and what goes wrong with disease states?”

HuBMAP will improve scientists’ ability to study stem cells and hopefully regrow damaged tissue. One of the projects includes the creation of a framework for studying the molecular markers of breast cancer and the creation of an atlas of senescent and senescent cells (SenNet).

The Human Cell Atlas won’t reveal every little secret in the human body, but it could provide a research basis, make future experiments easier and save lives. As Dana Beer, from Columbia University, Tell the Atlantic, “Think about what the presence of the genome has done in biology: We can find genes that cause disease, sequence tumors, customize medicine,” says Beer. I think the human cell atlas would have the same effect. And we need it to understand our own genome.”

Scientists have been able to sequence DNA from cancerous tissue samples. With just a few clicks on the computers, researchers using the human cell atlas are able to reverse engineer existing cells. According to the AtlanticThis “may help cancer biologists better classify tumors into distinct types, and develop more effective treatments.”

With the help of bioinformatics experts At the Center for Supercomputing at the University of Pittsburgh, Carnegie Mellon University, and Stanford University, the collected information will be uploaded to a digital cloud and converted into a map.

Information from over 600 labs will be sent to the bioinformatics team. After the data is commented out, it will be uploaded to a hybrid cloud that is maintained locally.

The team will then work to shape the genetic and protein signatures of healthy cells into a comprehensive map that can be seen by millions of medical people.

per bitwire“This project has the potential to impact Alzheimer’s disease and aging research and make a significant difference in the direction of future medical research,” said Kay Metis, director of the SeNet Program at the University of Pittsburgh.